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August 18 (Reuters) - Wall Street's main indexes hit their lowest in two weeks on Tuesday, pressured by losses in heavyweight technology stocks, while fading hopes for a U.S.-Iran peace deal sustained gains in oil prices and kept government bond yields at multi-year peaks.[.N] At 13:30 EDT, the Dow Jones Industrial Average was down 0.17% at 53,367.72. The S&P 500 was down 0.55% at 7,702.65, and the Nasdaq Composite was down 1.14% at 26,341.41.

The top three S&P 500 percentage gainers:

• Targa Resources Corp. , up 7.6%

• Ulta Beauty Inc , up 5.6%

• Intuit Inc. , up 5.5%

The top three S&P 500 percentage losers:

• Coherent Corp. , down 11.8%

• Ciena Corporation , down 10.4%

• Teradyne, Inc. , down 10.2%

The top three NYSE percentage gainers:

• Weave Communications, Inc. , up 31.7%

• Haemonetics Corp , up 17.0%

• UGI Corporation , up 11.8%

The top three NYSE percentage losers:

• Klarna Group PLC , down 21.1%

• Fabrinet , down 20.7%

• Vishay Precision Group, Inc. , down 12.2%

The top three Nasdaq percentage gainers:

• Profusa Inc , up 166.9%

• IP Strategy Holdings Inc , up 150.1%

• Aixcrypto Holdings Inc , up 126.7%

The top three Nasdaq percentage losers:

• Lucas GC Ltd , down 82.1%

• Ucloudlink Group Inc , down 35.3%

• Zenta Group Co Ltd , down 34.9%

• EyePoint Inc : BUZZ - Falls after experimental drug misses goal, brokerages cut ratings

• DocGo Inc : BUZZ - Slips on tepid quarterly results, narrower annual outlook

• Baidu Inc : BUZZ - Fall after downbeat Q2 revenue

• Corebridge Financial Inc :

• Equitable Holdings Inc :

• Brighthouse Financial Inc :

• Lincoln National Corp : BUZZ - Life insurance stock weakness after Mark Walter headlines overdone, Evercore says

• Dynatrace Inc : BUZZ - Up after $1.25 bln convertible offering prices

• Duolingo Inc : BUZZ - Gains after D.A. Davidson upgrades rating, hikes price target

• Amylyx Pharmaceuticals Inc : BUZZ - Soars as blood sugar drug succeeds in late-stage trial

• Einride AB : BUZZ - Gains on upbeat forecast, Tesla partnership

• Norwegian Cruise Line Holdings Ltd : BUZZ - Falls as Mizuho downgrades stock to 'neutral'

• Amer Sports Inc : BUZZ - Up after raising annual forecasts

• Prenetics Global Ltd : BUZZ - Rises on Q2 revenue jump

• Pliant Therapeutics Inc : BUZZ - Rises after FDA grants fast-track tag to experimental cancer drug

• Klarna Group PLC : BUZZ - Drops after trimming revenue and volume outlook

• BioMarin Pharmaceutical Inc : BUZZ - Up after agreeing to buy drug developer in deal worth up to $490 million

• Home Depot Inc : BUZZ - Rises on quarterly sales beat

• Weave Communications Inc : BUZZ - Jumps on Francisco Partners' takeover deal

• Barrick Mining Corp :

• Newmont Corp :

• Gold Fields Ltd :

• Harmony Gold Mining Company Ltd : BUZZ - Gold miners fall as bond yields surge to highest levels in decades

Index RIC Index name Percent

change %

S&P 500 -0.55

S&P 500 Information -1.9

Technology

S&P 500 Utilities 0.46

S&P 500 Consumer 0.11

Discretionary

S&P 500 Materials -0.6

S&P 500 Industrials -1.23

S&P 500 Communication -0.42

Services (Sector)

S&P 500 Financials 0.48

S&P 500 Real Estate 0.2

S&P 500 Health Care 1.61

S&P 500 Consumer Staples 1.31

S&P 500 Energy 1.52

(Compiled by Rajarshi Roy and Varun Sahay)